Grey’s Anatomy: Every Main Character Who Was Killed Off (& Why)

Grey’s Anatomy has gained a reputation for killing some of its main (and most beloved) characters instead of giving them satisfying endings, so who dies in Grey’s Anatomy? Grey’s Anatomy follows the basic premise of medical dramas, focusing on the lives of surgical interns, residents, and attendings as they balance their professional and personal lives, which more often than not overlap and create a lot of drama inside and outside Seattle Grace Hospital (now Grey Sloan Memorial Hospital). Grey’s Anatomy is led by Meredith Grey (Ellen Pompeo), who started her journey as an intern at Seattle Grace Hospital alongside other characters who went on to become audience favorites.